/// <summary>
/// 捕获鼠标
/// </summary>
/// <param name="hwnd"></param>
/// <returns></returns>
[DllImport("user32.dll", SetLastError = true)]
public static extern bool SetCapture(IntPtr hwnd);
/// <summary>
/// 释放鼠标
/// </summary>
/// <returns></returns>
[DllImport("user32.dll", SetLastError = true)]
public static extern bool ReleaseCapture()

Control.Capture;

Cursor cursor;
private void pictureBox1_MouseDown(object sender, MouseEventArgs e)
{
    Bitmap bitmap = Properties.Resources._111;
    cursor = new Cursor(bitmap.GetHicon());
    pictureBox1.Cursor = cursor;
    SetCapture(pictureBox1.Handle);
    bitmap.Dispose();
}
private void pictureBox1_MouseUp(object sender, MouseEventArgs e)
{
    cursor.Dispose();
    ReleaseCapture();
    pictureBox1.Cursor = Cursors.Default;
}